anti-WDR77 antibody

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  • Alternative name

    Androgen receptor cofactor p44, HKMT1069, MEP 50, MEP50, Methylosome protein 50, Nbla10071, p44, p44/Mep50, RP11 552M11.3, WD repeat domain 77, WDR77 antibody

  • Catalog
    A009503
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA
  • PurificationImmunogen affinity purified
  • ImmunogenWD repeat domain 77
  • Product Description specificalNon-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
  • Gene nameWDR77
  • locationCytoplasm,Nucleus
  • Uniprot IDQ9BQA1
  • Calculated M.W.50kDa




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