anti-UBE2A antibody

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  • Alternative name

    HHR6A, HR6A, RAD6 homolog A, RAD6A, UBC2, UBE2A, Ubiquitin carrier protein A, Ubiquitin protein ligase A antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC
  • PurificationImmunogen affinity purified
  • Immunogenubiquitin-conjugating enzyme E2A (RAD6 homolog)
  • IHCImmunohistochemistry of paraffin-embedded human lymphoma using A009163(UBE2A antibody) at dilution of 1:50
  • Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A009163(UBE2A antibody) at dilution of 1:600
  • Recommended dilutionWB : 1:200-1:2000;IHC:1:20-1:200
  • Product Description specificalAccepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
  • Gene nameUBE2A
  • locationCytoplasm,uclear chromatin
  • Uniprot IDP49459
  • Calculated M.W.17kDa
  • Observed M.W.17 kDa

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