Asprosin controls the mechanism of blood sugar

Asprosin is produced by white adipose tissue, a shear body at the end of profibrillin C.
A protein hormone that peaks in the blood of people and mice.

Figure 1: Asprosin regulates glucose and insulin release as the first messenger

Asprosin induces glucose formation in the liver through cAMP (Cyclic Adenosine monophosphate cyclophosphate) as a second messenger.
Asprosin generated in fat tissue into the liver combined with corresponding receptors become complex, adjust the G protein activated activated (GS), so that the GS protein activation of adenylate cyclase (AC), make the ATP pyrophosphate generated off cAMP as a second messenger activation of G protein - cAMP - PKA.
This leads to rapid release of glucose into the blood circulation, thereby promoting insulin production in islet B cells.
When the insulin concentration is too high, the immune isolation is produced, the glucose release in the liver is reduced, and the corresponding islet B cell insulin release is reduced.
For NPS patients, the pathway cannot be completed to show hypoglycemia.

Found in humans and mice by immune and genetic means improving insulin resistance function lack pathology revealed Asprosin with reductions in glucose and insulin and decrease hepatic glucose release.
There is also a link to Neonatal Progeroid Syndrome(NPS).

Figure 2: schematic diagram of human profibrillin N - end structure domain

Asprosin is closely related to human diabetes and NPS, in order to facilitate the scientific researchers to detect, Iraq by science and technology staff has developed people Asprosin Elisa kit, welcome the masses of scientific research personnel of choose and buy.

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