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Alternative name
Sim antibody
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Catalog
A008321
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityRat, Human, Mouse
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Applications Tested/SuitableELISA,WB,IF
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PurificationProtein A+G purification
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Immunogenstromal interaction molecule 1
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPlays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375). Involved in enamel formation (By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (By similarity).
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Gene nameSTIM1
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Uniprot IDP84903
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Observed M.W.80-90 kDa
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