Human TGFB2 ELISA Kit

Alternative name
Human TGF-beta-2 ELISA Kit;Human BSC-1 cell growth inhibitor ELISA Kit;Human cetermin ELISA Kit;Human glioblastoma-derived T-cell suppressor factor ELISA Kit;Human G-TSF ELISA Kit;Human polyergin ELISA Kit;Human LAP ELISA Kit;Human LDS4 ELISA Kit;Human TGF-beta2 ELISA Kit;Human transforming growth factor beta 2 ELISA Kit;Human transforming growth factor beta-2 ELISA Kit;Human prepro-transforming growth factor beta-2 ELISA Kit;
Catalog
E037918
species
Human
GeneTGFB2
Standard Curve
Other Species Mouse Tgfb2 ELISA Kit Bovine TGFB2 ELISA Kit Chicken TGFB2 ELISA Kit Porcine TGFB2 ELISA Kit Rat Tgfb2 ELISA Kit
SpecificityThe Human TGF beta 2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human TGF beta 2 proteins within the range of 31.2 pg/ml - 2000 pg/ml.
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
SensitivityThe minimum detectable dose of Human TGF beta 2 is typically less than 10 pg/ml.
Intended UseHuman TGFB2 ELISA Kit allows for the in vitro quantitative determination of TGFB2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the assay: The Human TGF beta 2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human TGF beta 2 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human TGF beta 2 coated on a 96-well plate. Standards and samples are pipetted into the wells and TGF beta 2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human TGF beta 2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of TGF beta 2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background: Transforming growth factor-beta 2 (TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma (POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured human anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
Human Latency-associated peptide Protein information
Uniprot ID TGFB2_HUMAN
Uniprot AC P61812; B4DKC5; P08112; Q15579; Q15581; Q4VAV9;
UniGene Hs.133379;
GeneID 7042
KEGG hsa:7042;
Human Latency-associated peptide Protein SEQUENCE
SEQUENCE 414 AA; 47748 MW; 7D9D569E0F4A07D0 CRC64;
MHYCVLSAFL ILHLVTVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL
TSPPEDYPEP EEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA
KEVYKIDMPP FFPSENAIPP TFYRPYFRIV RFDVSAMEKN ASNLVKAEFR
VFRLQNPKAR VPEQRIELYQ ILKSKDLTSP TQRYIDSKVV KTRAEGEWLS
FDVTDAVHEW LHHKDRNLGF KISLHCPCCT FVPSNNYIIP NKSEELEARF
AGIDGTSTYT SGDQKTIKST RKKNSGKTPH LLLMLLPSYR LESQQTNRRK
KRALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC
PYLWSSDTQH SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI
EQLSNMIVKS CKCS
UCSC uc001hlm.4; human.;

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Human TGFB2 ELISA Kit