Human TNFRSF6B ELISA Kit

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  • Alternative name

    Human Decoy receptor 3 ELISA Kit;Human DCR3 ELISA Kit;Human decoy receptor for Fas ligand ELISA Kit;Human M68 ELISA Kit;Human TR6 ELISA Kit;Human DJ583P15.1.1 ELISA Kit;Human M68E ELISA Kit;Human TNF receptor superfamily member 6b ELISA Kit;Human tumor necrosis factor receptor superfamily member 6B ELISA Kit;Human decoy receptor 3 variant 1 ELISA Kit;Human decoy receptor 3 variant 2 ELISA Kit;Human tumor necrosis factor receptor superfamily, member 6b, decoy ELISA Kit;

  • Catalog
    E011404
  • species
    Human
  • GeneTNFRSF6B
  • Standard CurveHuman TNFRSF6B ELISA Kit
  • SpecificityNatural and recombinant human DCR3
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity Sample For quantitative detection of human DCR3 in cell culture supernates, serum and plasm
  • Intended UseHuman TNFRSF6B ELISA Kit allows for the in vitro quantitative determination of TNFRSF6B , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: Human DCR3 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for DCR3 has been precoated onto 96-well plates. Standards(sf21, V24 - H300) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for DCR3 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human DCR3 amount of sample captured in plate. Background: Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-inducedapoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.
  • Human Tumor necrosis factor receptor superfamily member 6B Protein information
  • Uniprot ID TNF6B_HUMAN
  • Uniprot AC O95407;
  • UniGene Hs.434878;
  • GeneID 8771
  • KEGG hsa:8771;
  • Human Tumor necrosis factor receptor superfamily member 6B Protein SEQUENCE
  • SEQUENCE 300 AA; 32680 MW; F90AEE33718449AF CRC64;

    MRALEGPGLS LLCLVLALPA LLPVPAVRGV AETPTYPWRD AETGERLVCA

    QCPPGTFVQR PCRRDSPTTC GPCPPRHYTQ FWNYLERCRY CNVLCGEREE

    EARACHATHN RACRCRTGFF AHAGFCLEHA SCPPGAGVIA PGTPSQNTQC

    QPCPPGTFSA SSSSSEQCQP HRNCTALGLA LNVPGSSSHD TLCTSCTGFP

    LSTRVPGAEE CERAVIDFVA FQDISIKRLQ RLLQALEAPE GWGPTPRAGR

    AALQLKLRRR LTELLGAQDG ALLVRLLQAL RVARMPGLER SVRERFLPVH

  • UCSC uc002yfz.4; human.;


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