anti-VAMP8 antibody

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  • Alternative name

    EDB, Endobrevin, VAMP 8, VAMP8 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB
  • PurificationImmunogen affinity purified
  • Immunogenvesicle-associated membrane protein 8 (endobrevin)
  • Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A009365( VAMP8 Antibody) at dilution of 1:300
  • Recommended dilutionWB :1:200-1:1000
  • Product Description specificalSNAREs, soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex (PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets (PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity).
  • Gene nameVAMP8
  • Uniprot IDQ9BV40
  • Calculated M.W.15kDa
  • Observed M.W.15 kDa

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