anti-WDR24 antibody

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  • Alternative name

    C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,WB,IHC,IF
  • PurificationImmunogen affinity purified
  • ImmunogenWD repeat domain 24
  • IHCImmunohistochemistry of paraffin-embedded human ovary using A009488(WDR24 antibody) at dilution of 1:50
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009488(WDR24 antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:500-1:5000;IP:1:200-1:2000;IF:1:10-1:100;IHC:1:20-1:200
  • Product Description specificalAs a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2 (PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
  • Gene nameWDR24
  • locationCytoplasm,nuleus
  • Uniprot IDQ96S15
  • Calculated M.W.102kDa
  • Observed M.W.102 kDa,88 kDa

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