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Alternative name
43 kDa ISG15 specific protease, hUBP43, ISG43, Ubl thiolesterase 18, UBP43, USP18 antibody
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Catalog
A009313
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenubiquitin specific peptidase 18
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Western BlotWB result of USP18 antibody(A009313) with MCF-7 cells .
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Recommended dilutionWB :N/A
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Product Description specificalCan efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms._x000D_Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins (PubMed:22170061).
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Gene nameUSP18
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locationCytoplasm,Nucleus
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Uniprot IDQ9UMW8
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Calculated M.W.43kDa,Observed 70kDa,43kDa
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Observed M.W.43 kDa, 70 kDa
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