-
Alternative name
BET3, BET3 homolog, TRAPPC3 antibody
-
Catalog
A008947
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse
-
Applications Tested/SuitableELISA,WB,IF,IHC,IP
-
PurificationImmunogen affinity purified
-
Immunogentrafficking protein particle complex 3
-
IHCImmunohistochemistry of paraffin-embedded human placenta using A008947(TRAPPC3 antibody) at dilution of 1:100
-
Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A008947(TRAPPC3 antibody) at dilution of 1:800
-
Recommended dilutionWB:1:200-1:2000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:10-1:100
-
Product Description specificalTRAPPC3 (trafficking protein particle complex 3, also known as Bet3) is a component of TRAPP, a complex involved in the tethering of transport vesicles to the cis-Golgi membrane. There are three TRAPP complexes identified in yeast with distinct roles: TRAPPI in ER-Golgi traffic, TRAPPII in intra-Golgi and endosome-Golgi traffic, and TRAPPIII in autophagy. Recently it has been proposed that at least two complexes exist in mammals. TRAPPC3 is the most conserved subunit of TRAPP and has been used to precipitate the intact tethering complex both from yeast and from human cells. It has also been reported that TRAPPC3 is required for Rabin8 centrosome trafficking and ciliogenesis. Expressed ubiquitously, TRAPPC3 protein is present in both membrane-bound and cytosolic forms. This antibody recognizes the endogenous 20-22 kDa TRAPPC3 in multiple cell lines. (15728249, 21273506, 23394947)
-
Gene nameTRAPPC3
-
Uniprot IDO43617
-
Calculated M.W.20kDa
-
Observed M.W.20-22 kDa
-