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Alternative name
Tubby like protein 3, Tubby related protein 3, TUBL3, TULP3 antibody
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Catalog
A009109
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogentubby like protein 3
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor using A009109(TULP3 antibody) at dilution of 1:100
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Western BlotSH-SY5Y cells were subjected to SDS PAGE followed by western blot with A009109(TULP3 antibody) at dilution of 1:800
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000
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Product Description specificalNegative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein- coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.
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Gene nameTULP3
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locationCell membrane,Cell projection,Cilium,Cytoplasm,Membrane,Nucleus,Secreted
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Uniprot IDO75386
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Calculated M.W.56kDa
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Observed M.W.60 kDa
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