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Alternative name
NOLA2 antibody
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Catalog
A005727
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenNHP2 ribonucleoprotein homolog (yeast)
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A005727(NHP2 antibody) at dilution of 1:100
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Western BlotA375 cells were subjected to SDS PAGE followed by western blot with A005727(NHP2 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalRequired for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
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Gene nameNHP2
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Uniprot IDQ9NX24
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Observed M.W.17-20kd
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