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Alternative name
C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS antibody
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Catalog
A009016
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IP,IHC,WB
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PurificationImmunogen affinity purified
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Immunogentransient receptor potential cation channel, subfamily C, member 4 associated protein
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer slide using A009016( TRPC4AP Antibody) at dilution of 1:50
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Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A009016( TRPC4AP Antibody) at dilution of 1:300
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Recommended dilutionWB:1:200-1:1000;IP:1:200-1:1000;IHC:1:20-1:200
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Product Description specificalSubstrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
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Gene nameTRPC4AP
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locationCul4A-RING E3 ubiquitin ligase complex,lasma membrane
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Uniprot IDQ8TEL6
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Calculated M.W.91kDa
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Observed M.W.91 kDa
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