anti-TRIB3 antibody

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  • Alternative name

    C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IP
  • PurificationImmunogen affinity purified
  • Immunogentribbles homolog 3 (Drosophila)
  • Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A008966(TRIB3 antibody) at dilution of 1:600
  • Recommended dilutionWB:1:500-1:5000;IP:1:200-1:2000
  • Product Description specificalDisrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
  • Gene nameTRIB3
  • locationNucleus
  • Uniprot IDQ96RU7
  • Calculated M.W.40kDa,observed 45-65kDa
  • Observed M.W.40-45 kDa

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