StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
PurificationImmunogen affinity purified
Immunogensynemin, intermediate filament protein
IHCImmunohistochemistry of paraffin-embedded human skeletal muscle using A008440(SYNM antibody) at dilution of 1:50
Western BlotY79 cells were subjected to SDS PAGE followed by western blot with A008440(SYNM antibody) at dilution of 1:1000
Recommended dilutionWB : 1:500-1:5000
Product Description specificalType-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.