-
Alternative name
IMP 3, IMP3, Intramembrane protease 3, Presenilin like protein 2, PSL2, SPP like 2A, SPPL2A antibody
-
Catalog
A008191
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogensignal peptide peptidase-like 2A
-
IHCImmunohistochemistry of paraffin-embedded human testis using A008191(SPPL2A antibody) at dilution of 1:50
-
Western Blothuman colon tissue were subjected to SDS PAGE followed by western blot with A008191(SPPL2A antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
IHC : 1:20-1:200
-
Product Description specificalSPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273).
-
Gene nameSPPL2A
-
Uniprot IDQ8TCT8
-
Calculated M.W.58kd
-
Observed M.W.58kd
-