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Alternative name
RAB7, RAB7B, Ras related protein Rab 7b antibody
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Catalog
A007044
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenRAB7B, member RAS oncogene family
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IHCImmunohistochemistry of paraffin-embedded human small intestine tissue slide using A007044( RAB7B Antibody) at dilution of 1:50
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Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A007044(RAB7B antibody) at dilution of 1:200
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalControls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
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Gene nameRAB7B
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Uniprot IDQ96AH8
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Observed M.W.26 kDa
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