anti-ATG4C antibody

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  • Alternative name

    APG4C, AUTL1, AUTL3 antibody

  • Catalog
    A000675
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,WB,IHC,IF
  • PurificationImmunogen affinity purified
  • ImmunogenATG4 autophagy related 4 homolog C (S. cerevisiae)
  • IHCImmunohistochemistry of paraffin-embedded human heart using A000675(ATG4C antibody) at dilution of 1:50
  • Western Blotmouse testis tissue were subjected to SDS PAGE followed by western blot with A000675(ATG4C antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalCysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
  • Gene nameATG4C
  • Uniprot IDQ96DT6
  • Observed M.W.52-55 kDa


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