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Alternative name
BIGM103, PP3105, SLC39A8, ZIP 8, ZIP8 antibody
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Catalog
A009643
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogensolute carrier family 39 (zinc transporter), member 8
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IHCImmunohistochemistry of paraffin-embedded human placenta using A009643(SLC39A8 antibody) at dilution of 1:100
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Western Blotmouse lung tissue were subjected to SDS PAGE followed by western blot with A009643(SLC39A8 antibody) at dilution of 1:800
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Recommended dilutionWB : 1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalSLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.
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Gene nameSLC39A8
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locationmembrane
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Uniprot IDQ9C0K1
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Calculated M.W.50kDa,Observed 50kDa and 90kDa
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Observed M.W.42-46; 75-90 kDa
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