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Alternative name
FAPP2 antibody
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Catalog
A006537
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenpleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
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IHCImmunohistochemistry of paraffin-embedded human kidney using A006537(PLEKHA8 antibody) at dilution of 1:50
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A006537(PLEKHA8 antibody) at dilution of 1:800
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalCargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
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Gene namePLEKHA8
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Uniprot IDQ96JA3
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Observed M.W.49kd
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