StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman, Mouse
PurificationImmunogen affinity purified
Immunogensmall nuclear ribonucleoprotein polypeptide G
IHCImmunohistochemistry of paraffin-embedded human breast cancer using A008078(SNRPG antibody) at dilution of 1:100
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A008078(SNRPG antibody) at dilution of 1:300
Recommended dilutionWB : 1:200-1:1000
Product Description specificalCore component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing.