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Alternative name
CHCR, MBLX39, MBXL antibody
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Catalog
A005041
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IHC,WB
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PurificationImmunogen affinity purified
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Immunogenmuscleblind-like 3 (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using A005041( MBNL3 Antibody) at dilution of 1:50
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Western Blotmouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A005041( MBNL3 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalMediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
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Gene nameMBNL3
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Uniprot IDQ9NUK0
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Observed M.W.38 kDa
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