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Alternative name
LNX, PDZRN2 antibody
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Catalog
A004814
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenligand of numb-protein X 1
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalE3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity). _x000D_Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
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Gene nameLNX1
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Uniprot IDQ8TBB1
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Observed M.W.70 kDa
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