StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
Immunogen3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
IHCImmunohistochemistry of paraffin-embedded human liver using A003928(HMGCL antibody) at dilution of 1:100
Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A003928(HMGCL antibody) at dilution of 1:300
Recommended dilutionWB : 1:200-1:2000
Product Description specificalKey enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.