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Alternative name
CIG, Cold insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, Fibronectin, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF antibody
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Catalog
A003122
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenfibronectin 1
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A003122(FN1 antibody) at dilution of 1:50
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Western BlotNIH/3T3 cells were subjected to SDS PAGE followed by western blot with A003122(FN1 antibody) at dilution of 1:500
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Recommended dilutionWB:1:200-1:2000
IP:1:200-1:1000
IHC:1:50-1:200
IF:1:20-1:200
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Product Description specificalFibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis. (PMID: 7276612; 12244123; 12847088)
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Gene nameFN1
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Uniprot IDP02751
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Calculated M.W.260kDa,observed 260kDa,70kDa,100kDa
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Observed M.W.250 kDa,70 kDa
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