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Alternative name
APG16L antibody
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Catalog
A000669
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP
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PurificationImmunogen affinity purified
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ImmunogenATG16 autophagy related 16-like 1 (S. cerevisiae)
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A000669(ATG16L1 antibody) at dilution of 1:500
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Recommended dilutionWB:1:200-1:2000;IP:1:200-1:1000
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Product Description specificalPlays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
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Gene nameATG16L1
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Uniprot IDQ676U5
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Calculated M.W.68kDa
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Observed M.W.63-71kd
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