-
Alternative name
MORT1 antibody
-
Catalog
A002941
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,IHC,WB,IP
-
PurificationImmunogen affinity purified
-
ImmunogenFas (TNFRSF6)-associated via death domain
-
IHCImmunohistochemistry of paraffin-embedded human lung cancer using A002941(FADD antibody) at dilution of 1:50
-
Western BlotHT-1080 cells were subjected to SDS PAGE followed by western blot with A002941( FADD Antibody) at dilution of 1:300
-
Recommended dilutionWB : 1:200-1:1000
-
Product Description specificalApoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
-
Gene nameFADD
-
Uniprot IDQ13158
-
Observed M.W.23 kDa
-