-
Alternative name
D4ST1 antibody
-
Catalog
A001694
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogencarbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
-
IHCImmunohistochemistry of paraffin-embedded human placenta using A001694(CHST14 antibody) at dilution of 1:50
-
Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A001694(CHST14 antibody) at dilution of 1:600
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalCatalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
-
Gene nameCHST14
-
Uniprot IDQ8NCH0
-
Observed M.W.45-50 kDa
-