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Alternative name
BACURD2, EDP1 antibody
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Catalog
A008817
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB
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PurificationProtein A+G purification
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Immunogentumor necrosis factor, alpha-induced protein 1 (endothelial)
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalSubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
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Gene nameTNFAIP1
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Uniprot IDQ13829
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Observed M.W.36 kDa
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