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Alternative name
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I antibody
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Catalog
A000006
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman,Mouse
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Applications Tested/SuitableELISA,WB,IHC
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PurificationProtein A+G purification
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Immunogeneukaryotic translation initiation factor 4E binding protein 1
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IHCImmunohistochemistry of paraffin-embedded human pancreas slide using A000006( 4EBP1 Antibody) at dilution of 1:50
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A000006(4EBP1 antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000;IHC : 1:20-1:200;IF : 1:20-1:200
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Product Description specificalEukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
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Gene nameEIF4EBP1
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Uniprot IDQ13541
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Calculated M.W.12kDa
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Observed M.W.15-24 kDa
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