anti-NENF antibody

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  • Alternative name

    CIR2, SPUF antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityMonoclonal Antibody
  • Host Mouse
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,IHC,WB
  • PurificationProtein A+G purification
  • Immunogenneuron derived neurotrophic factor
  • IHCImmunohistochemistry of paraffin-embedded human cerebellum using A005661(NENF antibody) at dilution of 1:50
  • Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A005661(NENF antibody) at dilution of 1:1000
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalActs as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).
  • Gene nameNENF
  • Uniprot IDQ9UMX5
  • Observed M.W.18 kDa

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