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Alternative name
Atriopeptidase, CALLA, CD10, DKFZp686O16152, Enkephalinase, EPN, membrane metallo endopeptidase, MME, NEP, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11 antibody
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Catalog
A005232
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman,Pig
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Applications Tested/SuitableELISA,IHC,WB
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PurificationProtein A+G purification
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Immunogenmembrane metallo-endopeptidase
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IHCImmunohistochemistry of paraffin-embedded human renal cell carcinoma using A005232(MME,CD10 antibody) at dilution of 1:100
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Western Blotpig kidney tissue were subjected to SDS PAGE followed by western blot with A005232( MME,CD10 Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200
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Product Description specificalMME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.
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Gene nameMME
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locationCell membrane
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Uniprot IDP08473
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Calculated M.W.86kDa,observed 100kDa
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Observed M.W.90-110 kDa
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