anti-Alpha-2-macroglobulin antibody

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  • Alternative name

    A2M, Alpha 2 M, alpha 2 macroglobulin, CPAMD5, DKFZp779B086, FWP007, S863 7, α-2M antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityMonoclonal Antibody
  • Host Mouse
  • Species ReactivityHuman
  • Applications Tested/SuitableELISA,IHC,WB
  • PurificationProtein A+G purification
  • Immunogenalpha-2-macroglobulin
  • IHCImmunohistochemistry of paraffin-embedded human liver slide using A000341( A2M Antibody) at dilution of 1:50
  • Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A000341(A2M antibody) at dilution of 1:1000
  • Recommended dilutionWB :1:500-1:5000;IP:1:200-1:2000;IF:1:50-1:500;IHC:1:20-1:200
  • Product Description specificalAlpha-2-macroglobulin, also known as α2-macroglobulin (α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
  • Gene nameA2M
  • locationSecreted
  • Uniprot IDP01023
  • Calculated M.W.163kDa,observed 185kDa
  • Observed M.W.185 kDa

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