-
Alternative name
ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C antibody
-
Catalog
A000304
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityMonoclonal Antibody
-
Host Mouse
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB,IF
-
PurificationProtein A+G purification
-
Immunogenaldolase C, fructose-bisphosphate
-
IHCImmunohistochemistry of paraffin-embedded human liver cancer tissue slide using A000304( ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
-
Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A000304(ALDOC antibody) at dilution of 1:10000
-
Recommended dilutionWB :1:5000-1:50000;IHC:1:50-1:500;IF:1:20-1:200
-
Product Description specificalFructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
-
Gene nameALDOC
-
locationmitochondrion,ytosol,xtracellular exosome
-
Uniprot IDP09972
-
Calculated M.W.39kDa
-
Observed M.W.40 kDa
-
Related products with anti-Aldolase C antibody