anti-Aldolase C antibody

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  • Alternative name

    ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityMonoclonal Antibody
  • Host Mouse
  • Species ReactivityHuman
  • Applications Tested/SuitableELISA,WB,IF
  • PurificationProtein A+G purification
  • Immunogenaldolase C, fructose-bisphosphate
  • IHCImmunohistochemistry of paraffin-embedded human liver cancer tissue slide using A000304( ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
  • Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A000304(ALDOC antibody) at dilution of 1:10000
  • Recommended dilutionWB :1:5000-1:50000;IHC:1:50-1:500;IF:1:20-1:200
  • Product Description specificalFructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
  • Gene nameALDOC
  • locationmitochondrion,ytosol,xtracellular exosome
  • Uniprot IDP09972
  • Calculated M.W.39kDa
  • Observed M.W.40 kDa

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