anti-CHOP; GADD153 antibody

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  • Alternative name

    C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP; GADD153, CHOP10, DDIT 3, DDIT3, GADD153 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityMonoclonal Antibody
  • Host Mouse
  • Species ReactivityHuman
  • Applications Tested/SuitableELISA,WB
  • PurificationProtein A+G purification
  • ImmunogenDNA-damage-inducible transcript 3
  • Western BlotTunicamycin treated HeLa cells were subjected to SDS PAGE followed by western blot with A001668( CHOP; GADD153 Antibody) at dilution of 1:1000
  • Recommended dilutionWB:1:500-1:5000
  • Product Description specificalCHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
  • Gene nameDDIT3
  • Uniprot IDP35638
  • Calculated M.W.20kDa,observed 30kDa,40kDa
  • Observed M.W.30 kDa

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