Human RARRES2 ELISA Kit

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  • Alternative name

    Human chemerin ELISA Kit;Human RAR-responsive protein TIG2 ELISA Kit;Human tazarotene-induced gene 2 protein ELISA Kit;Human TIG2 ELISA Kit;Human HP10433 ELISA Kit;Human retinoic acid receptor responder 2 ELISA Kit;Human retinoic acid receptor responder protein 2 ELISA Kit;Human retinoic acid receptor responder (tazarotene induced) 2 ELISA Kit;

  • Catalog
    E007947
  • species
    Human
  • GeneRARRES2
  • Other Species Mouse Rarres2 ELISA KitBovine RARRES2 ELISA KitHamster RARRES2 ELISA Kit
  • SpecificityNatural and recombinant human Chemerin
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 20pg/ml
  • Intended UseHuman RARRES2 ELISA Kit allows for the in vitro quantitative determination of RARRES2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Principle of the assay: human Chemerin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for Chemerin has been precoated onto 96-well plates. Standards(E.coli, V17-S163) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Chemerin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human Chemerin amount of sample captured in plate. Background: Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1(also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What's more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
  • Human Retinoic acid receptor responder protein 2 Protein information
  • Uniprot ID RARR2_HUMAN
  • Uniprot AC Q99969; Q7LE02;
  • UniGene Hs.647064;
  • GeneID 5919
  • KEGG hsa:5919;
  • Human Retinoic acid receptor responder protein 2 Protein SEQUENCE
  • SEQUENCE 163 AA; 18618 MW; A96EB7D0999EC3DB CRC64;

    MRRLLIPLAL WLGAVGVGVA ELTEAQRRGL QVALEEFHKH PPVQWAFQET

    SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA

    CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF

    PGQFAFSKAL PRS

  • UCSC uc003wha.4; human.;


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