Mouse Bglap ELISA Kit

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  • Alternative name

    Mouse bone Gla protein ELISA Kit;Mouse BGP ELISA Kit;Mouse gamma-carboxyglutamic acid-containing protein ELISA Kit;Mouse Bglap1 ELISA Kit;Mouse OC ELISA Kit;Mouse OG1 ELISA Kit;Mouse mOC-A ELISA Kit;Mouse bone gamma carboxyglutamate protein ELISA Kit;Mouse osteocalcin ELISA Kit;Mouse bone gamma carboxyglutamate protein 1 ELISA Kit;

  • Catalog
    E045945
  • species
    Mouse
  • GeneBglap
  • Other Species Human BGLAP ELISA KitBovine BGLAP ELISA KitCanine BGLAP ELISA KitGoat BGLAP ELISA KitChicken BGLAP ELISA KitHorse BGLAP ELISA KitMonkey BGLAP ELISA KitPorcine BGLAP ELISA KitRabbit BGLAP ELISA KitRat Bglap ELISA Kit
  • SpecificityThis assay has high sensitivity and excellent specificity for detection of Mouse BGLAP. No significant cross-reactivity or interference between Mouse BGLAP and analogues was observed.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity0.78 pg/ml
  • Intended UseMouse Bglap ELISA Kit allows for the in vitro quantitative determination of Bglap , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical
    Introduction: Osteocalcin is a noncollagenous protein found in bone and dentin. It is secreted by osteoblasts and thought to play a role in mineralization and calcium ion homeostasis. It has been stipulated that osteocalcin may also function as a negative regulator of bone formation, although its exact role is unknown. As osteocalcin is manufactured by osteoblasts, it is often used as a biochemical marker, or biomarker, for the bone formation process. It has been routinely observed that higher serum-osteocalcin levels are relatively well correlated with increases in bone mineral density (BMD) during treatment with anabolic bone formation drugs for osteoporosis, such as Forteo. In many studies, Osteocalcin is used as a preliminary biomarker on the effectiveness of a given drug on bone formation. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to OT. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated 2 antibody preparation specific for OT and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain OT, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of OT in the samples is then determined by comparing the O.D. of the samples to the standard curve.
  • Mouse Osteocalcin Protein information
  • Uniprot ID OSTCN_MOUSE
  • Uniprot AC P86546; P04641;
  • UniGene Mm.389459;
  • GeneID 12096
  • KEGG mmu:12096;
  • Mouse Osteocalcin Protein SEQUENCE
  • SEQUENCE 95 AA; 10549 MW; ADCE40516ECEF971 CRC64;

    MRTIFLLTLL TLAALCLSDL TDAKPSGPES DKAFMSKQEG NKVVNRLRRY

    LGASVPSPDP LEPTREQCEL NPACDELSDQ YGLKTAYKRI YGITI

  • UCSC uc008puy.2; mouse.;



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