anti-ZW10 antibody

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  • Alternative name

    HZW10, KNTC1AP, ZW10 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman
  • Applications Tested/SuitableELISA,WB
  • PurificationImmunogen affinity purified
  • ImmunogenZW10, kinetochore associated, homolog (Drosophila)
  • Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A009760( ZW10 Antibody) at dilution of 1:1000
  • Recommended dilutionWB:1:500-1:5000;IP:1:200-1:2000
  • Product Description specificalEssential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:15029241).
  • Gene nameZW10
  • locationCentromere,Chromosome,Cytoplasm,Cytoskeleton,Endoplasmic reticulum,Kinetochore,Membrane
  • Uniprot IDO43264
  • Calculated M.W.90kDa
  • Observed M.W.88-90 kDa

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