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Alternative name
ZKSCAN3, dJ874C20.1, KIAA0426, ZF47, ZFP306 antibody
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Catalog
A009646
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IF
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PurificationImmunogen affinity purified
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Immunogenzinc finger with KRAB and SCAN domains 3
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A009646(ZKSCAN3 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000;IF:1:10-1:100
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Product Description specificalTranscriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
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Gene nameZKSCAN3
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locationCytoplasm,Nucleus
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Uniprot IDQ9BRR0
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Calculated M.W.62kDa
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Observed M.W.61-65kd
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