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Alternative name
Fliz1, ZC3H8, ZC3HDC8 antibody
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Catalog
A009605
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenzinc finger CCCH-type containing 8
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A009605( ZC3H8 Antibody) at dilution of 1:2000
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Recommended dilutionWB:1:1000-1:10000
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Product Description specificalActs as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
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Gene nameZC3H8
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Uniprot IDQ8N5P1
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Calculated M.W.34kDa
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Observed M.W.35 kDa
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