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Alternative name
CCN family member 4, CCN4, WISP 1, WISP1, WISP1c, WISP1i, WISP1tc, Wnt 1 induced secreted protein antibody
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Catalog
A009514
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IP,WB
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PurificationImmunogen affinity purified
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ImmunogenWNT1 inducible signaling pathway protein 1
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IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A009514( WISP1 Antibody) at dilution of 1:50
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Western Blotrat kidney tissue were subjected to SDS PAGE followed by western blot with A009514( WISP1 Antibody) at dilution of 1:600
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Recommended dilutionWB:1:200-1:2000;IHC:1:20-1:200;IP:1:200-1:2000
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Product Description specificalDownstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
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Gene nameWISP1
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locationSecreted
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Uniprot IDO95388
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Calculated M.W.40kDa,Observed 45kDa
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Observed M.W.40-46 kDa
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