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Alternative name
EX1, FERM domain containing 6, FRMD6, Willin antibody
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Catalog
A009510
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenFERM domain containing 6
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IHCImmunohistochemistry of paraffin-embedded human liver cancer using A009510(Willin antibody) at dilution of 1:50
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Western BlotRecombinant proteins were subjected to SDS PAGE followed by western blot with A009510( Willin Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000;IHC:1:20-1:200
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Product Description specificalWillin, also known as FRMD6 or human Expanded (hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
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Gene nameFRMD6
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locationCell membrane,Cytoplasm,Membrane
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Uniprot IDQ96NE9?
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Calculated M.W.72kDa
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