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Alternative name
B7 H4, B7h.5, B7H4, B7S1, B7X, FLJ22418, PRO1291, Protein B7S1, RP11 229A19.4, VCTN1, VTCN1 antibody
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Catalog
A009461
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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ImmunogenV-set domain containing T cell activation inhibitor 1
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor tissue slide using A009461( VTCN1 Antibody) at dilution of 1:200
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Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A009461( VTCN1 Antibody) at dilution of 1:600
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Recommended dilutionWB :1:200-1:2000；IHC:1:50-1:500
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Product Description specificalNegatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
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Gene nameVTCN1
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locationCell membrane
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Uniprot IDQ7Z7D3
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Calculated M.W.27kDa,observed 60kDa
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Observed M.W.55-65 kDa
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