anti-VPS53 antibody

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  • Alternative name

    FLJ10979, HCCS1, hVps53L, pp13624, VPS53 antibody

  • Catalog
    A009448
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB
  • PurificationImmunogen affinity purified
  • Immunogenvacuolar protein sorting 53 homolog (S. cerevisiae)
  • Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A009448(VPS53 antibody) at dilution of 1:300
  • Recommended dilutionWB :1:500-1:5000;IP:1:200-1:2000
  • Product Description specificalActs as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
  • Gene nameVPS53
  • Uniprot IDQ5VIR6
  • Calculated M.W.96kDa
  • Observed M.W.95-97 kDa


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