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Alternative name
FLJ14848, hVPS33B, VPS33B antibody
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Catalog
A009436
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat,Zebrafish
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenvacuolar protein sorting 33 homolog B (yeast)
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IHCImmunohistochemistry of paraffin-embedded human kidney using A009436(VPS33B antibody) at dilution of 1:100
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Western Blotmouse testis tissue were subjected to SDS PAGE followed by western blot with A009436(VPS33B antibody) at dilution of 1:500
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Recommended dilutionWB :1:500-1:5000;IHC:1:50-1:200;IF:1:10-1:100
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Product Description specificalMay play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).
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Gene nameVPS33B
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locationCytoplasmic vesicle,Endosome,Lysosome,Membrane
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Uniprot IDQ9H267
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Calculated M.W.71kDa
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Observed M.W.71 kDa
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