-
Alternative name
VIL, VIL1, Villin, villin 1 antibody
-
Catalog
A009406
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF
-
PurificationImmunogen affinity purified
-
Immunogenvillin 1
-
IHCImmunohistochemistry of paraffin-embedded human small intestine tissue slide using A009406( VIL1 Antibody) at dilution of 1:200
-
Western Blotmouse kidney tissue were subjected to SDS PAGE followed by western blot with A009406(VIL1 antibody) at dilution of 1:2000
-
Recommended dilutionWB :1:1000-1:10000;IHC:1:50-1:8000;IF:1:20-1:200;IP:1:200-1:1000
-
Product Description specificalVillin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
-
Gene nameVIL1
-
locationCell projection,Cytoplasm,Cytoskeleton
-
Uniprot IDP09327
-
Calculated M.W.93kDa
-
Observed M.W.93 kDa
-