anti-uPA antibody

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  • Alternative name

    ATF, PLAU, U plasminogen activator, uPA, URK antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IP,IF
  • PurificationImmunogen affinity purified
  • Immunogenplasminogen activator, urokinase
  • IHCImmunohistochemistry of paraffin-embedded human skin using A009267(uPA antibody) at dilution of 1:50
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A009267(uPA antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:500-1:5000
  • Product Description specificalPLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1 (PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder (QPD).
  • Gene namePLAU
  • locationSecreted
  • Uniprot IDP00749
  • Calculated M.W.50kDa
  • Observed M.W.54 kDa

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