-
Alternative name
UNC5C, unc 5 homolog C (C. elegans), UNC5H3, Protein unc 5 homolog 3, Protein unc 5 homolog C antibody
-
Catalog
A009263
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse ,Rat
-
Applications Tested/SuitableELISA,WB
-
PurificationImmunogen affinity purified
-
Immunogenunc-5 homolog C (C. elegans)
-
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A009263(UNC5C-Specific antibody) at dilution of 1:1000
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalUNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.
-
Gene nameUNC5C
-
Uniprot IDO95185
-
Calculated M.W.103kDa,Observed 50kDa,103kDa
-
Observed M.W.50kd,103kd
-