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Alternative name
TSG, TWSG1 antibody
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Catalog
A009120
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB
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PurificationImmunogen affinity purified
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Immunogentwisted gastrulation homolog 1 (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded mouse brain tissue slide using A009120( TWSG1 Antibody) at dilution of 1:50
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Western BlotSH-SY5Y cells were subjected to SDS PAGE followed by western blot with A009120( TWSG1 Antibody) at dilution of 1:300
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Recommended dilutionWB:1:200-1:1000;IHC:1:20-1:200
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Product Description specificalMay be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
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Gene nameTWSG1
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locationSecreted
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Uniprot IDQ9GZX9
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Calculated M.W.25kDa,Observed 45kDa
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Observed M.W.45 kDa
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