-
Alternative name
BHLHa39, Dermis expressed protein 1, Dermo 1, DERMO1, twist homolog 2 (Drosophila), Twist related protein 2, TWIST2 antibody
-
Catalog
A009119
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman, Mouse
-
Applications Tested/SuitableELISA,WB
-
PurificationImmunogen affinity purified
-
Immunogentwist homolog 2 (Drosophila)
-
Western BlotNIH/3T3 cells were subjected to SDS PAGE followed by western blot with A009119(TWIST2 antibody) at dilution of 1:500
-
Recommended dilutionWB:1:200-1:2000
-
Product Description specificalBinds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
-
Gene nameTWIST2
-
locationCytoplasm,Nucleus
-
Uniprot IDQ8WVJ9
-
Calculated M.W.18kDa,Observed 21kDa,65kDa
-
Observed M.W.21kDa, 60 kDa
-